Repeated implantation failures after IVF are cases in which, despite the satisfactory number and good quality of embryos, there is no pregnancy in more than two IVF cycles.

When there is a low number and quality of embryos, we consider that the embryos are the main cause of failure. However, even in these cases, an examination can be made to verify whether there are other factors of failure.

The examination includes:

  • Hysteroscopy, i.e. check of the uterine cavity for endometrial polyps, adhesions, fibroids. Along with the diagnosis, the treatment performed is their removal.
  • Endometrial biopsy to check for infections
  • Check for thrombophilia (blood clotting) and treatment with aspirin or heparin
  • Pre-implantation diagnosis of fetuses (PGS)
  • Assisted embryo hatching if the casing is thick
  • Improved embryo transfer technique
  • Tubal re-section in case of hydrosalpinx
  • Differentiation of stimulation protocol
  • Test for sperm DNA fragmentation
  • Karyotype of both parents
  • Intrauterine injection of platelet-rich plasma (PRP)
  • Uterine scratching
  • Control of the mother’s body weight
  • Psychological support for the parents